The brief from the Christie was for a new building to replace an existing outdated facility and to house to the largest early clinical trials unit in the world, the largest chemotherapy unit in the UK and a new private patients unit. This building was to be of the highest architectural quality, create a strong new entrance to the hospital and achieve a BREEAM ‘Excellent’ Rating. The building has been designed to have a relationship with the existing buildings on site, both visually and physically. The building has been orientated to relate to the adjacent buildings on the site, and create a stronger and more legible main entrance point to the hospital.